My understanding is that tetrahydrofuran (THF) reacts with oxygen to produce explosive peroxides, BHT is often added to stabilize it and best practice is to store it under a nitrogen blanket. I am the lab manager in a neuroscience research lab and we need to use THF to delipidate mouse brains for whole brain clearing to image on a lightsheet microscope.
My question is how do make a system to purge the headspace and replace it with nitrogen gas without braking the bank? Use of THF is going to very low and sporadic. Should we just withdraw it with a syringe, dispose of it with EHS every 3-6 and order fresh? Get a nitrogen tank and do the balloon trick, or is unscrewing the cap and flowing N2 into the bottle and recapping sufficient? Or is the only safe method a $200 cap with a tank and regulator?
Please help. I am tired of making decisions today.