u/MarsupialParticular7

I know that Clomipramine is a TCA antidepressants but it is also the most potent SNRI's available on the market , after being on 75mg for 4 weeks , bumped to 112.5mg last week and my energy levels are finally back to baseline ( I had sever chronic fatigue due to my depression ) , my anxiety is also very manageable and my thoughts are so quiet for god remembers how long ... , my derealization is much better too

All in allw Clomipramine is a very succes to me after trying over 20meds over the course of 5 years .

I am also on olanzapine 5mg ( instead of Seroquel 300mg wich made me a zombie 24/7 ) , olanzapine is really good so far at 5mg , Depakote 500mgx2 , and lastly Tianeptine 12.5mg x 3 a day and 50mg Amisulpride for major depression .

This combo is really bringing me back to life after years in a dark hole ...

Whats ur experience guys with clomipramine ?

I have been on clomi for close to 4 weeks now , started with 50mg then 75mg and now 150mg since 2 days ago my last bump .

Things are really starting to feel okay , the constant rumination and dread feeling is very manageable now , my thoughts are no longer running 180miles an hour , I feel grounded and present instead of drowlling in my own thoughts 24/7 , my emotions are a bit back , I can focus on the external world , my anxiety is down since I don't remember when ... Btw mine is weed induced .

Im really excited about the upcoming weeks , I am also on depakote 500x2 a day , Olanzapine 5mg ( 1 week ) instrad of Seroquel ( Seroquel was such a bad experience ... ) , my paranoid thoughts and over self conscious are way manageable too , and lastly Im also on 50mg Amisulpride at night & Tianeptine to help with dysthymia and major depression .

Please get help if you can , I spent years in this mental prison . Help is always available and many people recovered just fine or even fully recovered with meds and other interventions.

I still have a long way to go , I need to fix my lifestyle add exercise and other things . Keep fighting guys .

Quick background of my long life battling major depression , chronic cannabis use wich led to paranoid thoughts , hyperexcitability , inner tension and feelings of unease , chronic anxiety and social anxiety , being overly self conscious , obsessive thoughts and fears / dread about pretty much everything , anhedonia & lack of pleasur in everything , mind won't shut down even at night ...

I was initially prescribed depakote ( 1500mg a day ) , Seroquel 300mg since my paranoia was a bit serious , clomipramine 75mg ( to help with anxiety and ocd ) ,low dose amisulpride 50mg , I had very mild success with this combo nothing life changing I could just cope with life , go to work , etc ...

Last week my doctor added Stablon ( tianeptine ) , wich is approved where i live for major depressive disorder , I am on 25mg morning , 12.5mg early afternoon , and 12.5 evening so total 50mg .

It has been nothing but a miracle , I can know what peace of mind is since ages , my focus is better , my social anxiety improved alot , my stress levels are way down and the most important thing is iM not abusing it at all and not thinking of doing so , I will keep taking my prescribed 50mg dose ( split ) , I think it also synergies with low dose amisulpride since my anhedonic tones and depressed thoughts improved alot alongside motivation .

I don't understand why some countries red flagged this med and made it unavailable ... Like poeple can abuse anything , morphine for exemple wich is an opiod too is available in the us and people still abuse it so why not ban it too ? I guess big pharma is fighting against anything that is not SSRI's or a profitable med ...

Anyone here on Stablon too ? ( Prescribed or self medicating within the therapeutic doses ) , would love to hear others exoeriences since very few people take this drug .