u/Many-Ask1932

It’s hard for me to still talk about this because of the medical gaslighting and suffering I went through this period of my life, but it’s important for people to know that this can happen, even though rare.

Medication Adverse Reaction History:

History of severe systemic adverse reaction to methadone and buprenorphine (Suboxone), including:
- QTc prolongation on ECG
- Severe edema requiring daily compression wrapping
- Debilitating lower extremity pain severely limiting mobility
- Recurrent cellulitis
- Hyperprolactinemia with amenorrhea (>1 year)
- Pituitary microadenoma identified during this period
- Medication-induced thyroid abnormalities (resolved after discontinuation)
- Worsening sleep apnea and sensation of air hunger despite normal oxygen levels
- Severe insomnia and cognitive impairment.
- Elevated D-dimer and abnormal laboratory values during exposure

Symptoms improved significantly (let’s be real, my symptoms completely disappeared) after discontinuation of these medications and recurred upon re-exposure.