u/LeesKeys

▲ 9 r/cll

Reactions to Venetoclax?

I'm beginning month three of my Gazyva+Venetoclax treatment. I've been ramping up the dosage of venetoclax for the past month. This week is my first week of the full dose, 400mg daily. Up until this latest ramp up, I haven't had any adverse reactions to oral therapy at all. Today, on my third day in the full dose, I've had stomach pains followed by diarrhea, followed by a calm stomach for the past hour. I'm wondering if others have had the same kind of experience, that is, no adverse reaction until getting to the full dose. If so, did the stomach pains and diarrhea persist? Did your digestive system eventually acclimate to the full dose? And if so, how long did that take?

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u/LeesKeys — 5 days ago