42M CRSwNP
2014 CT results showed needed surgery despite max therapy.
2018
FESS, Septoplasty, turbinate reduction
6 month low dose macrolide therapy
Roxithromycin
12 weeks Clarithromycin
Exhausted ALL antibiotics high doses an long courses
8000mg or more cumulative corticosteroids within the past 5 years.
50mg prednisilone daily for 1 week then 25 daily 2 weeks then 12.5mg daily 1 week. Dexamethasone courses
Maximal topical nasal flush
Budesonide respules + xylitol every night
Cycle baby shampoo in it
Did mupirocin and tobarmycin rinses
7 months Nucala
MRI
Jan 2025 (after 5 week oral steroids)
This is after Nightly nasal rinses with pulmicort respules
Polyps unilateral? But drs and ENT were not worried because it says ethmoids but still red flag unilateral.
CT May 2026
Shows advanced sinus disease despite max therapy
Surgeon recommended
Total functional rhinoplasty + left and right mega anstrostomies
Not to touch ethmoids or sphenoid due to biofilm and will treat separately. I assumed ethmoidectomy and sphenoidectomy as the area is opacified and mri had polyps.
I suffer severe brain fog, malaise, heaviness and pressure behind eyes. Depression and anxiety from feeling like I can’t read or function. I do always have green, or yellow come out of my flushes. Now it’s white sometimes brown which could be blood but wanted to rule out fungal?
Based on my scans and history. What do you suspect? And does this correlate to my symptoms? (I also have severe cervical stenosis)
What would be the best treatment options for me?
In Australia Dupixent isn’t covered and lymphoma risk as well concerns me.
Scans [My CT and MRI scans on IMGUR](https://imgur.com/gallery/ct-mri-scans-of-sinuses-gPhZ7Q8)