u/JudiciousJackalope

Might not look like a significant number, but having tracked my weight through various diets and whatnot over 30 years, this is the lowest number I've ever seen. The lowest since high school. And the previous all-time-low was from my early 30s, when I had almost no responsibilities or distractions and was able to intensely focus on diet and exercise to where I was eating nothing but salads and running marathons, and still that only got me to 243.8 lbs.

This puts me at ~64 lbs down from my study starting weight, and I'm only on week 36 of the TRIUMPH-6 80-week open-label lead-in period. I literally cannot imagine what I'll look or feel like in another 44 weeks (or another 80 weeks if I get randomized into the high-dose maintenance arm).