Stage 4 melanoma. Seizure2 after 3rd and 4th cycle of immunotherapy.
My husband was diagnosed with stage 4 with Mets to brain, lung, liver and bone in Feb 2026. A stage 1 mole was removed from his scalp in 2012. So yes, it came back to him after 15 years almost.
He started with ipi/nivo comb in Feb. He got seizure the day right after his 3rd treatment where his oncologist flipped ipi/nivo dose to the aggressive more stronger one. Then he got second seizure 4 days after his 4th cycle which is the safer dose as the first two round.
Now he’s on dexamethasone 12mg a day. His oncologist stopped his immunotherapy because of the brain tumor swelling resulted in seizures. She wants him to be on steroid with weekly lab. His total bilirubin is 5. She wants the number to go down a little then start him on targeted therapy pill. But he only has BRAF class 2 mutation.
Can anyone please share some of your thoughts? Thank you very much!!