

A theoretical compound I designed that could be up to 60,000 times the potency of morphine, and 600 times as potent as fentanyl. A dose equivelent to 10mg of morphine would be 167ng and a lethal dose would be 3.33ug. This compound would be at the theoretical maximum binding affinity, efficacy and intrinsic activity of the mu-opioid receptor and no antagonist would have a high enough affinity to displace it.