u/Important-Dream438

Hi!

Just a quick question regarding neutropenia investigation (27F)

I had an incidental finding on routine bloods which continued to drop over subsequent tests to 0.7, where it sat for a few months and has hovered between 0.7-1.6 since.

My haematologist ordered flow cytometry which I am still awaiting the result for after 6 weeks (I don’t believe I have the symptoms of LGL).

My haematologist referred me to rheumatology due to ANA 1:320 speckled + raynaud phenomenon.

Auto-immune bloods came back clear apart from a low-normal C4 at 18mg/dl, and negative ANA 1:80. Im suspecting it’s not a rheumatological issue? (I haven’t had an appointment with rheum since these results).

Question:

If the flow cytology comes back negative what would the next step be from the haematology pov?

TIA!

Hi all!

Hoping this is a safe space.

Earlier this year I had a stress # of the R femur. Routine bloods highlighted neutropenia (which continued to decline to 0.7 after repeat testing). ANA came back as 1:320 fine speckled. Viral screen, negative.

I was referred to Haematology who ordered flow cytometry- and referred me to rheumatology.

Rheumatologist ordered repeat MRI, ANA and auto-immune panel bloods and C3/C4.

I have a plethora of symptoms inc:
Raynaud phenomenon
Significant fatigue
Sun sensitivity
Swelling of eyelids, fingers and feet
?malar rash (it looks like flushing over my cheeks and nose)
Persistent low grade fever
Intermittent lymph node swelling in groin
Hives
*neutropenia

(This is all I can think of right now)

Panel bloods came back negative, and ANA dropped to 1:80 (speckled). C3, normal. C4 18mg/dl, low normal. Repeat MRI showed healed NOF but showed unilateral sacroiliitis. (Still awaiting haem flow cytology result after 6 weeks!)

I haven’t had an appointment with my rheumatologist since these bloods have come back negative. I’m apprehensive that my panel bloods are clear, that I will be discharged from Rheumatology. Could this be something auto-immune? I have no idea!

Any thoughts as to what could be going on from your experience/knowledge? Any advice?

Would really appreciate any input;

Kindest Regards-
a person who knows nothing about the rheum/haem world!

Edit: typo!