u/INphys15837

For background, I was diagnosed in 2021 with high levels anti PM/SCL 100 & 75 antibodies and lower levels but still high cenp A and RNP A. Diagnosis is systemic scleroderma with minor ILD and overlap of myositis. Used to take cellcept but after a nasty histoplasmosis episode that resulted in 9 day hospitalization 1.5 years ago, I now take plaquenil.

Normally I function pretty well. While there is always some level of pain, I still garden, hike, swim, bike. However, in the last week, I have felt just one shoulder area skin tighten up. Otherwise my overall skin score has been really good. There is also an underlying sharp pain occasionally. I'm hoping it is just an injury, but can tightening happen on only one side and in one location?