u/Federal-Scratch-2500 — reddlx

1. Classical piston-based pipetting
Uses a mechanically driven piston or syringe. Liquid is aspirated and dispensed through displacement, with the piston creating vacuum and pressure to control volume.

2. Pressure-over-liquid pipetting
Uses controlled air pressure and vacuum on a liquid reservoir. Vacuum pulls liquid in, pressure pushes it out—no mechanical displacement, flow is controlled indirectly via air and valves.

If you had to choose for your system, how would you compare them in terms of:

Precision
Repeatability
Cost
Endurance
Maintenance
Flexibility
Speed

👉 Which one would you go with — and what’s the biggest trade-off in your experience?

Also curious: where do you see pipetting technology heading in the next few years?