(Translated by Google Translate. Apologies for any spelling errors)
Good afternoon everyone.
I was studying the disease and read about the medication Piascledine, which appears to be a combination of avocado and soy.
Below are the benefits I read about. Do you think it could be a potential treatment for lichen sclerosus?
If there is valuable information here, I intend to bring it to my dermatologist to enrich this information.
What Piascledine does to your skin (Summary)
- Blocks the "Infinite Scar": It inhibits the TGF-β protein, which is what gives the order for the skin to harden (sclerosis). Without this excess order, the skin stops turning into that "rigid plaque".
- Reduces "Silent" Inflammation: It decreases interleukins (especially IL-1), which keep the skin red, irritated, and itchy. - Restores Elasticity: It stimulates the production of younger, more flexible collagen, helping to eliminate that "cigarette paper" or "porcelain" appearance.
Avocado/Soybean Unsaponifiables (ASU) is a unique compound, defined by law and pharmaceutical patents as a mixture of fractions of avocado oil (1 part) and soybean oil (2 parts). Therefore, no other food in the world "manufactures" this specific combination.
- Blocks the Skin's "Cement": The combination inhibits the TGF-β protein, which is the "villain" that causes the skin to produce hard collagen. Avocado and soybean together are much more potent at blocking this protein than each one in isolation
- Activates Cleansing: The mixture helps activate enzymes that "eat" old and rigid collagen, allowing the skin to breathe and regain suppleness.
Avocado Only: Nourishes, but does not soften sclerosis.
Soybean Only: Reduces inflammation slightly, but does not regenerate tissue.
Avocado + Soybean (The Combination): Attacks the cause of hardness and helps restore elasticity.
In this context: it is understood that both must be consumed together or the expected effect in treating lichen sclerosus will not occur.
I don't know how much this would actually affect lichen sclerosus, since even medications seem to take a while to show any benefit, but just as we try to attack it in every way with diet, exercise, and a healthier lifestyle to reduce this inflammation, I believe this combination could add a lot.
Any extra information will be welcome, feel free to comment.