I’ve been on Metformin for about a month and a half for insulin resistance. I started at 500 mg once daily and now I’m at 500 mg twice a day.
I also have Hashimoto's thyroiditis.
I’ve never had issues tolerating medications before, but this has been… an experience.
Symptoms didn’t hit too hard initially but lately I’m:
feeling full/bloated pretty often
getting random bouts of diarrhea (the urgent kind where I need a bathroom ASAP)
noticing it’s pretty unpredictable
I haven’t made major diet changes yet (I know, I know — that’s on me). I also don’t eat the greatest… definitely a bit of a sugar addict, which probably didn’t help me get here. I’m not exercising much either, but I am trying to work up to it.
Honestly, I’d really like to hear from people who:
had similar symptoms early on made diet adjustments and saw improvement or just stuck it out and things eventually normalized? Or didn’t make changes and things didn’t normalize?
We’re also considering adding Wegovy, so I’m especially curious how people’s stomachs handled that combo with metformin.
Not looking for perfection or guarantees — I know everyone’s different. Just trying to get a realistic sense of whether this phase passes and what actually helped.
Would really appreciate any experiences or tips 🙏