Undergoing STC Day -7
Hi everyone!
New person here - 32F, diagnosed with MDS in January 2026.
MDS EB2 10% blasts
Karyotype 46 XX
Molecular ASXL1 RUNX1 PHF6 U2AFI
IPSS-M Very High Risk
Thankfully, we've hit the jackpot with our donor - 10/10 match. I'm going to be forever grateful to that person when this is over - I am cautiously optimistic given the journey we've been on.
I had a course of CPX-351 in February to lower the blast cells and prepare for my STC, that resulted in a 40 night stay as my neutrophils stayed between 0.0 and 0.1 for weeks.
On the 03/04, I entered hospital to begin my Allogenic Protocol.
My first 4 days of chemo were rough, and my body didn't tolerate Amsacrine very well - sickness, shivers. Day -10 I spiked a 38 temperature, which prompted fever procedures (anyone else get temp worries when the thermometer comes out?)
Tomorrow are my TBI sessions, with a 7 hour gap.
I've got ATG for days -5, -2, -1
I've also got Mesna, and Cyclophosphamide for days -4, -3
Then, I start ciclosporin -1.
Then, new birthday 16/04 🎉 where I also start Mycophenolate after my transplant
So far, my mind has been pretty active but my body has been feeling like it's been hit by a bus, and the tiredness just comes our of nowhere and takes me out for a good 4/5 hour nap at times.
Does anyone have any suggestions, or support, for the coming days?