I was on 150mg XL for 3.5 months and after 6-8 weeks it had finally kicked in and was great, except for during the week before my period, to which I also have PMDD. I know Wellbutrin isn't necessarily one of the main prescriptions to treat PMDD, but I was prescribed it for my MDD, which it worked great for and a little bit for PMDD. Before Wellbutrin my PMDD week would be a 1/10 in terms of mental health, and after I think it ranges from 3/10-6/10, which is still an improvement, but not enough. So my doc and I decided to try upping to 300mg first before trying something else.
I've been on 300mg xl for 4 weeks now and the first 2 or so weeks were absolutely brutal. Nausea, dizziness, sensitive stomach, no appetite, light sensitivity, mood swings, irritability/anger, demotivation/anhedonia, and shaky hands. At 4 weeks, some of the side effects have gone away except for absolutely no appetite, sensitive stomach, and demotivation/anhedonia/emotional blunting. I ironically just don't care about anything at all. Nothing excites me. I also kind of can't feel my feelings. I also think I've been having some memory issues. I'm thinking of trying to stick it out a little longer since it took 6-8 weeks for the 150xl to work for me, but I can't lie that I'm scared and discouraged.
What if I go back to 150xl and it no longer works for me? Anybody who increased to 300mg xl, how long did it take to work for you? If you had anhedonia as a side effect, did it go away? I know Wellbutrin is used for appetite suppression, but I really hope my appetite comes back.