u/Effective_Piece251

Jack-O Valentine (Guilty Gear) She has a split personality, one serious and the other is just a goofy cartoon character who loves candy. In-game her animations feel straight out of a cartoon and she is really expressive.

Jessie (Pokemon) She’s just the lady equivalent of a mustache twirling, Saturday morning cartoon villain who wants to be bad but sucks at. She has an abundance of comical, cartoony moments and in Sun and Moon they amped it up to 11, her facial expressions are gold

Doronjo Yatterman (Yatterman) She’s alot like Jessie, I wouldn’t be surprised if Pokemon took inspiration from Doronjo for Jessie. She’s also the girl in the team of two guys that is comical villain who fails all the time and has many comedic moments

Leon Kennedy (Resident Evil) This guy is serious when he needs to be, but when he opens his mouth, he’s a complete dork. His lines are so corny that’s it’s hilarious

Karlach (Baldurs Gate 3)

Spawn (Spawn)

Ghost Rider (Marvel)

Faust (Guilty Gear)

Rapunzul’s frying pan (Tangled)

Kushina’s frying pan attack (Naruto Ultimate Ninja Storm)

Spike fighting with a broom (Cowboy Bebop the movie)

Mira Naigus (Soul Eater)

Dosu (Naruto)

Hush (DC)

Nicole Watterson (The Amazing World of Gumball)

Elastigirl (The Incredibles)

Chili Heeler (Bluey)

Yor Forger (Spy x Family)

Of course my examples are taken a bit extreme, less extreme examples are also welcome

Sinthea Schmidt (Marvel comics) She is Red Skull’s daughter

Brittney (Smiling Friends) The Boss’ girlfriend

Psuedo-Palutena (Kid Icarus Uprising) She is a clone of Palutena made by Dynthos, I can’t find an image of her full body, but it looks just like regular Palutena’s

Balalaika with her men of Hotel Moscow (Black Lagoon)

She cares about them deeply and sees them all as brothers and comrades. She cares about them so much that >!when one of her men were murdered by the main villains who are two children, she nearly starts a war in the city looking for them and kills one of them brutally!<

Ursula (The Little Mermaid)

She genuinely loves her two Eels and she crashes out during the final battle when they die

General Grevious (Star Wars The Clone Wars)

Okay this is more so specifically just this scene because Greivous absolutely hates the droids, but this one scene where his pet alien monster Gor dies, Grievious is genuinely sad, you can hear him whimper when he says “Gor…?” And then he yells in anger

Voice lines from the character Ryuko Matoi in the game Kill la Kill IF

The Ojou-sama noblewoman laugh

Sailor Mars (Sailor Moon)

Queen (Deltarune)

Karin Kanzuki (Street Fighter)

Frieza (Dragon Ball Z)

Risky Boots (Shantae)

(Ninjago) In an episode, the Ninja have to compete in a dance competition to get the fangblade, for their performance, they dance to the Weekend Whip, the main theme song of Ninjago

(Steven Universe) “We are the Crystal Gems” is a song that was made by Steven that he sung to Garnet, Ameythst and Pearl as a kid

(Arcane) In one scene, Jinx could be heard listening to her theme song “Get Jinxed”

Juno’s Mediblaster (Overwatch) It has the option to heal people, it can be used to attack enemies and heal allies

The fart gun (Despicable Me) Does exactly what the name implies, shoots farts

Many inator rays by Dr Doofenshmirtz (Phineas and Ferb) some of his inators shaped like guns don’t do things

Ms Monarch (Venture Bros)

Seth (Street Fighter 5)

Lythero’s Rouge the Bat (Youtube)

Midna (Legend of Zelda Twilight Princess)

Conquest (Invincible)