u/DunnoNgl

My question is basically that.

I've thought that I could make him lack ISG15 because I read it in a science magazine that it's possible it basically makes you overcome viral illnesses more easily. Then I searched a bit about it and apparently it also causes dermatologic issues, which isn't something I want to add. And also brain calcification??

So I searched a bit more and decided giving him another mutation that slows down AIM2 would be good. But apparently that would make him practically defenseless against bacterial sickness, which I ALSO don’t want

Is there another mutation I can give him to deal with that without adding too many serious side effects? Or should I give this branch up and try to find something else? Anything would help