MTHFR gene mutation - should I continue taking folic acid or switch to methylated folate for conception?
I recently found out I have the following mutations for the MTHFR gene from my 23andme raw data:
rs1801133 (C677T) = AG
rs1801131 (A1298C) = GT
Google says that these result in moderately reduced enzyme function. I am trying to conceive and have been taking a prenatal with folic acid since October since folic acid is proven to prevent neural tube defects in babies development. Now I’m concerned that my body won’t be breaking down the folic acid properly. It doesn’t sound like I don’t have the complete inability, but unsure about how well my body does process it. Should I switch to a prenatal that has methylated folate instead? Or is it worth it to continue taking the folic acid with the hope that my body can process it despite having a slight mutation? Really trying to get a better understanding of what my results mean and what action to take moving forward.
Thank you in advance!