Hey everyone,
I'm working on a retrosynthesis project for my Organic Chemistry class and I've hit a wall.
The Goal:
We have to pick an organic compound and retro-synthesize it back to commercially available starting materials that cost less than $10 per gram.
The Problem:
I've attached an image of my target molecule. I'm doing okay breaking down most of the framework, but I am really struggling with the picture above I've tried different ways to cut the molecules and i always hit a dead end, it feels like I'm close but when it comes down to it the stereocenter is either in the wrong place or the starting material is to expensive
I don't know what kind of reaction or sequence to use to ensure I maintain that specific stereocenter without messing up the rest of the molecule.
Does anyone have any advice on which specific disconnection I should be looking at, or a name reaction that preserves this stereochemistry that I might be forgetting? Any nudges in the right direction would be hugely appreciated!