Canine SCC?
Hello,
I have an interesting case I wanted to share and get some opinions on. I am sending several slides to a pathologist next week but wanted some thoughts.
Signalment and history: 8yr M Cane Corso. Presenting for an annual exam and owner is concerned about a mass on his dorsal neck. It was found last year and has grown a lot over the last couple months. No FNA was taken prior.
The mass is 5-6cm in diameter, cutaneous, firm, and the same color as his skin. There is mild alopecia in the center. The mass is non-painful and the surrounding skin is normal.
I did an FNA and removed ~6 mL of moderately thick brown/hemorrhagic fluid. The mass shrunk slightly but was still very firm. These photos are from a sample of the fluid. Differentials are an SCC w/necrotic center vs keratin inclusion cyst.
I am finding frequent singular nucleated keratinocytes with moderate aniscytosis and anisokaryosis. There is a lot of necrotic debris and pyknotic neutrophils. I found very rare sheets of 5-10 epithelial cells. This is an image of one sheet with a nucleated keratinocyte next to it.
I wish I would’ve taken more photos. I can definitely get more next week. Thanks!