Mounjaro has been life changing
I do want to prefix this by saying that I know it's not a cure, and judging by other posts here, it doesn't work for everybody, but wow, this stuff has made me improve by 85-90%.
I started taking this just under a month ago for weight loss. Was previously on Saxenda for about a year, which did a little for weight loss and nothing for anything else, then it stopped working completely. I had got up to 150kg and so I knew I needed to do something.
My main LC symptoms were severe fatigue (with crashes that could go on for weeks), nausea and migraines. I was primarily housebound, but would go into work for 5-6 hours a week. Generally was stuck around 1,000-2,000 steps a day.
I started taking Mounjaro, and 2ish days after the first dose, I woke up and felt... Normal. Just like I did before I got sick. I wasn't exhausted, I wasn't nauseous and my head wasn't sore... Huh. The weirdest thing of all, was that I had energy. Like, I was able (and wanted) to go and do things.
It's now been almost 4 weeks and I do 5,000-10,000 steps a day, I've been going out places, back to work almost full time and I haven't had a single crash in that entire month. It's also working great for weight loss (the added activity helps I'm sure!)
As I said though, I don't think it's a cure. I do find, that especially at night or in the morning, I'm often run down (runny nose and going hot or cold) and I do sometimes feel like I'm getting a migraine but it never comes. I'm assuming this medicine is suppressing this somehow, and that I'll need to stay on it forever to feel like this, but right now, it's an amazing step forward.
I'd also like to add, that I reckon a key to a lot of this for me is in the gut. If I don't eat (or eat very little) during the day, I feel even better. I'm being smart and sticking to 1,800+ calories - because who wants scurvy, but I've found a couple of protein coffees can sort me out for an entire day of feeling amazing.