u/Blender-Expert

Hi everyone. I’m trying to understand the reduction of nitriles to primary amines using Sn/HCl (Not Stephen's Reduction by SnCl2). I’ve come across references to this method, but I’m a bit confused about how exactly the mechanism works and under what conditions this reaction is preferred over other reducing agents like LiAlH₄ or catalytic hydrogenation.

Could someone explain the mechanism of this reduction? Also, please provide resources or references that cover this reaction.

Thanks in advance!

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u/Blender-Expert — 9 days ago