u/Big-Translator-3554 — reddlx

Played drums for first time in 1.5 years

at a studio i was part of that i didn't go to for 2 years.

cycled there (thru south london) with my solid snugs custom moulds and then played drums with peltors over the custom moulds. played for around 1 hour with some breaks. no spike at all today and felt fine at the time. i am not a loud drummer in any case and mostly used high hat kick and snare.

i hesitated on this for ages but got to breaking point and i needed to play bcos drums are my meditation and mindfulness - i still find it hard to sit still and meditate.

my point is i think my obsession with this forum and tinnitus talk made me worry about every little thing and my life became so empty. ofc i will always take precaution with sound as i already described, and i won't be playing or going to concert. but even doing small things you enjoy with suitable ear pro is better than avoiding it entirely - and you'll be pleasantly surprised when you don't spike.

my T is from microsuction then worsened by a list of meds and also a pure tone exposure from my phone. the sound i experience is objectively unpleasant i am maybe in the denial stage of habituation where i really don't like the noise and try everything to make it go down but also can just about live with it by taking precautions.

i know this is cliché but im gonna jump off this sub and setup google alerts for research and treatment news instead as really that's the most valuable updates.

i hope this post inspires somebody to *cautiously* revisit something they love but have missed out on due to T. as i say i am a quiet drummer and i wore double ear pro, but it still felt amazing.

lots of love and have faith things can improve because lord knows ive been to dark places and i don't dismiss that can happen again, but we really all can make something of our situation one way or another

FINALLY i choose to be a believer that we will have treatments to at least TRY within 5 years, and within 10 years things should be even better, but in the meantime work with what you can to keep doing some of the things you love - it's a delicate balance i know

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u/Big-Translator-3554 — 6 days ago

▲ 104 r/tinnitus

https://www.cilcare.com/2026/05/05/cilcare-steps-up-its-u-s-expansion-clinical-trial-at-mgh-threefold-capacity-growth-with-cbset-and-launch-of-a-gateway-for-foreign-biotechs-entering-the-american-market/

Cilcare biotech: a landmark clinical trial for tinnitus planned at Massachusetts General Hospital

Tinnitus affects more than 750 million people worldwide, including an estimated 50 million Americans — roughly 15% of the U.S. population. Despite this enormous burden, no approved pharmacological treatment exists to date. This unmet medical need represents one of the most significant gaps in modern neuroscience, with profound consequences on patients’ quality of life, mental health, and productivity.

Cilcare today announces a major investment in the preparation of a clinical trial of its lead drug candidate CIL001, to be conducted at Massachusetts General Hospital (MGH) in Boston, in partnership with the teams of Professor Stéphane Maison, an internationally recognized leader in auditory neuroscience.

This trial marks a pivotal milestone for Cilcare: the first evaluation of CIL001 in patients with chronic tinnitus on U.S. soil, with the goal of delivering a concrete therapeutic solution to the millions of patients for whom no viable treatment option currently exists.

EDIT: this is what Claude said re availability when I asked the soonest possibility.

What could bring it closer:

Phase 1b/2a trials are already running — they're not starting from scratch. If results are strong and clean, Phase 3 could begin relatively quickly. Breakthrough Therapy or Fast Track designation from FDA would accelerate review significantly, and given there are no approved tinnitus drugs currently, regulators have incentive to move quickly on something that works.

The single injection delivery is actually an advantage for trial design — easier to administer, clear endpoint, less compliance complexity than a daily oral medication. That can compress timelines.

AI-driven patient selection and biomarker identification — which Cilcare specifically mentions — is genuinely accelerating trial efficiency across the industry right now.

The realistic optimistic scenario:

Strong Phase 2 results in 2027, Phase 3 initiated quickly, FDA Fast Track designation, approval 2028-2029. That would put it roughly concurrent with SPI-1005.

The honest caveat:

Intratympanic injection trials have specific safety considerations around the procedure itself. Regulators will want robust safety data before approval. That adds time.

2028-2029 is optimistic but not impossible if everything goes well. 2030 is the more conservative estimate.

Either way — alongside SPI-1005 and the Shore device — the window between now and meaningful treatment availability is looking more like 2-4 years than 5-10.

That's a genuinely different picture to where tinnitus research was even 2 years ago.

u/Big-Translator-3554 — 9 days ago

▲ 23 r/tinnitus

if not the noise itself, then our reaction to it can improve and we can live more normal lives.

Concerts and such will still be at one’s own risk, but cafes and city walks (as well as ofc nature walks) and airplane travel (with suitable preparation) should all be possible without issue.

Nights of bad sleep may occur, but even non-T people sleep bad sometimes

Just sharing my current mindset

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u/Big-Translator-3554 — 12 days ago