u/Big-Caterpillar-807

While browsing the wiki page about uploading (https://pantheon-amc.fandom.com/wiki/Deep\_Scan), a question came to mind regarding the condition of uploaded individuals that we see in the series,

all of them appear to have had healthy brains prior to uploading. And I wondered what would happen if someone with a neurological condition like microcephaly, Tay-Sachs disease, or a similar disorder were to undergo the upload process. How might their condition influence the procedure itself, or their experience as an uploaded intelligence?