Anyone else tried Mestinon?
I've had chronic vomiting for 9 years now and still don't have a firm diagnosis, but I'm reasonably confident in my theory that I have gastroparesis caused by EDS. Recently, my CFS specialist put me on Mestinon.
I'm on 60mg 3x a day and his next suggestion is transitioning to a sustained release tablet and gradually increase to 2 of those a day. Once I got up to 60mg 3x a day, I saw dramatic improvements - I was previously vomiting nearly everything I ate and my current record is now 4 days with no vomiting.
In the beginning, it made my hunger UNBEARABLE - it was painful and nauseating - but that has subsided. Other than that, the only real awful side-effect is the urinary urgency, but I can deal with that.
Recently, though, it seems to have diminishing returns, as well as I have zero appetite and have to force myself to eat because no food is appealing to me.
TL;DR: What are others' experience with Mestinon?