u/After-Justice

Need some guidance/opinions regarding my father’s prostate cancer case and upcoming surgery.

My father is 60 years old and currently has no symptoms. He was diagnosed with prostate adenocarcinoma (Gleason 4+4 = 8, Grade Group 4). Surgery planned is radical prostatectomy.

We recently got the PSMA PET-CT report and I wanted help understanding how serious/localized this sounds from people who may have gone through similar situations.

Important PET-CT findings/conclusion:

- PSMA avid lesion in left peripheral zone/apex of prostate
- Lesion indenting anterior wall of rectum with loss of fat plane
- No PSMA avid lymph nodal metastases
- No distant metastases seen
- Subtle right 5th rib lesion mentioned but considered likely benign/non-specific due to no abnormal PSMA uptake

Doctors are still proceeding with radical prostatectomy with curative intent.

Questions:

  1. Does this sound like locally advanced but still operable disease?
  2. How common is recurrence in cases like this after surgery?
  3. For people with Gleason 8 + negative PSMA spread, how was long-term recovery/outlook?
  4. How difficult was urinary recovery after catheter removal?
  5. Did anyone require radiation/hormone therapy later even after surgery?

Trying to stay realistic but also hopeful since the PET didn’t show obvious distant spread.

Would appreciate honest experiences/advice.

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u/After-Justice — 8 days ago