Release of methylphenidate, how to slow it more ?
Hi, i've somes problems with the release of concerta. I take 54mg, but i feel effect too fast, after 10minutes i'm anxious, not at the thérapeutic dose, because i remember i was relax at 20mg ir of ritalin.
So it's like the libération xr is anarchic, i try to eat, but it's change nothing. I want to warn you i have somes problems digestion, i digest probably too fast, but more slow with concerta. It's good because it's was the opposite with methylphenidate xr from ritalin medikinet, and quasym it was in middle, between concerta and others xr.
Concerta generic were worsen than medikinet and ritalin xr. I'm very sensitive because lot of people dont feel différent with différents form like ritalin and medikinet, but for me i think it's from digestion. 30mg of ritalin la make me sleep and anxious like my dose of concerta at morning a little, and the effect was good only with an other dose of 30. Also, i try an other time 60mg xr and it was similar than 20mg ir ritalin, but even if it's xr, the durability was ridiculous, and i keep anxiéty and vasoconstriction with ritalin xr at all doses.
Medikinet and quasym were little similars for me, better than ritalin xr, and more similars than one dose of ritalin ir when the dose is effective. Medikinet 5/10 make sleepy, 20 mg anxious and vasoconstriction, so i was scared to level UP, but one day i take 20/20 morning and at 12h, but i was Bad too, and i tried 20 at night, just little bellet in my mouth because i was scared, and after all finally, and may be the absorption was différent, but i was relax.
So After i tried medikinet 40mg at morning with food like they said, and it was worse than without food, without food it was really good, i was super relax, my mind was open, muscle not contracted, i can speak like i want because it's my big problem. But when methylphenidate permit to circulate blood on my brain i'm ok. The worse is to be on the middle, to low to be good, but too high which provocate anxiéty.
My psychiatre dont know why really i'm sensitive like this. Before to take methylphenidate, i had others psychosomatic problem, digestion, i've difficulties to take weight even i eat a lot, i prefer eat little portion than big because i'm not good if i take all food in one. I digest also really fastly.
We said usully concerta don't depend of digestion, but i think it's wrong, because it's active on our intestines, and i feel my intestines are contracted, except when the dose is effective and efficient to relax my brain and after my body.
I know also when i go on a too high dose, it's nearly 60mg quasym once or concerta 72 once, i felt like zombie, but not stress, just apathic during first Time, and good 8/9 hours later.
With ritalin ir, i feel effect more fast, in 5min, during one hour. 5mg three time make me sleep, 10mg make me anxious and give me vasoconstriction and cold in hand like medikinet 20mg, so it's little logical. But, 20mg it's ok, but if course it's impossible for me ton have a constant effect, because if take 20mg again i'm too high, if i take 10mg too late i'm off and sleepy, and i have to maintain the dose with successive doses of 10mg/5 more than 5/6 during the day.
The solution is concerta, but something wrong. Imagine today, i was cold during all day because of my dose of morning 54mg, and i don't feel really the dose honestly, sometimes it's really good, but i can't erase the sides effects. And it's strange to have more with 54mg than 20mg ir ritalin because it's supposed to be more in one time.
I have also 10mg ir booster, but it's sometimes usleess. The finally proof of my digest problem, was the différents effects on 10mg ir ritalin at 2 hours after and 20mg xr ritalin, because it's supposed to be the same, but i feel like a crash on 20mg fastly than ir, and nether 2nd peak.
I see sommes people break the ir release of concerta when they put it on little glass of water diring little time, but i hésitate to do this now, because i'm fed up. I see with medikinet xr, even it was différent i have relax effect when i put in my mouth, quasym and ritalin ir too.
Concerta i'm feel with palpitations at first hours, and more calm at maximum effect at afternoon. So i think heart failure are not link for me with high dose, because i'm better on Maximum, and i feel same effect at the enf with crash, palpitations anxiéty. And one time i took 54mg morning, and was with vasoconstriction all day, like overdose and anxiéty, so it's was strange to be more calm with an other dose of 54mg during afternoon, my palpitations dissapear, mind clear, relax, and body warm
So i don't understand nothing of my body do insinse, but there is a problem. The methylphenidate i usefull, but my body destroy it, i don't know how it's possible to make more retard the retard release, if someone have somes advises i'm open, other thing usual like eat that or that, more protéines, fibres, because i digest food fastly, it's make nothing.
The better regime i did in past was carnivor diet because there is not fiber agressives with my intestines, and the digestion is more slow, but even if with this, the effect was little shy.
I have also did a lot of analyses, but all was ok, exclude acidity stools when i was eating more fibres, but i never make test with other diet. Also little deficiency on b12, but when i take more and régulate it on analyses, it make zéro change. Also in urine, i've tested but on private lab cathecolamines in urine, and all was ok except adrénaline little more than base, so they speak after about like others forums inside here, slow comt, but honestly i'm not really satisfy with this explanations. I try méthionine and same like they said, but make me nothing, not Bad but just spend my money.
Also i've seen little molécules do something, i can count it in my hands, it was huperzine a with little more saliva because it's like i'm on fight flight réaction all day except when methylphenidate is active on all areas brain at the good dose. But the effects wasn't durable. Also, sulbutiamine, when ritalin xr make me in Bad way with palpitations, sulbutiamine was like to permit to réduce the dose slowly and réduce my anxiéty, but make me sleepy little, and the effect aren't reproductible.
I've seen also effects with yohimbine, not for sexual life, i try it for saliva, but it make me nervous and i can't sleep with it.
I try also medic, ISRS was Bad, make me apathic, venlafaxine, seroplex, and also anxiolytic but it was usleess.
I use also a product usefull on Raynaud syndrom and dryness mouth which permit to decrease the activation of sympathic nervous system , called name pilocarpine in hospital. I had saliva , but i was like the molécule forced physically, and methylphenidate when it's effective permit to increase saliva with other way with relaxation of brain and after the body. With pilocarpine i was not good, because there is a lot of sides effects, and it's an obligation to take it 3 Times day, and it's also expensive in France
The better effect was probably with only with a vitamine, niacin flush. It's strange but i was clear on my mind without brain fog, for explanations i use it once After a bad réaction on quasym every mounth, but one time i take niacin After the crash sensation, and suddenly the fog dissapear, it's like someone open the window with methylphenidate but the release it's not adapted, and niacin permit to open the light on the room.
But i prefer to don't take it anymore, because of skin réaction of course, but also because of probably effects which studies show insuline résistance. And the effect wasn't durable.
So now i'm lost. I think there is something to do on my digestion. If it was possible in France to take patch of methylphenidate i'm open, but unfortunatly it's impossible...